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Clinical Trial

For additional details on ongoing clinical trials with OQL011, please visit


Hand-Foot Skin Reaction (HFSR) is a common adverse event induced by Vascular Endothelial Growth Receptor Inhibitor (VEGFRi) treatment in cancer patients. The main purpose of this study is to evaluate the safety and efficacy of OQL011 compared to vehicle ointment in treating patients with moderate to severe VEGFRi-associated HFSR. This study will also identify an optimal dosage for Phase III study and explore the pharmacokinetics profile of OQL011 in HFSR patients.


  • Patient must be age 18 years of age or older.

  • Patient must have a confirmed cancer diagnosis for which VEGFRi treatment is indicated, and must be currently under VEGFRi-based anti-cancer therapy with stable dosage for ≥ 1 week.

  • Patients on pain medications are allowed provided they have been on stable dosage in the past 1 week and is going to continue at the same dosage.


Dr. Robert Tyler

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